Drugs of abuse assays cross-reactivity manual

 · November Product Spotlight: Toxicology Drugs of Abuse Testing. TOX/See from Bio-Rad, Hercules, Calif, is a one-step, handheld, point-of-care test device for the qualitative detection of 14 drugs or drug metabolites in human urine. The TOX/See product portfolio includes specific tests for emerging drugs of abuse, such as oxycodone. The assay uses specific antibodies, which can detect amphetamine and/or methamphetamine in urine with minimal cross-reactivity to various over-the-counter structurally unrelated compounds. The assay is based on the competition of an enzyme glucosephosphate dehydrogenase (G6PDH) labeled drug and the drug from the urine sample for a fixed amount. An enzyme donor-drug conjugate is prepared by linking the drug molecule to the enzyme donor fragment. Competitive binding reaction results in the formation of active enzyme and consequently coloured product, which is directly proportional to the concentration of the drug present. This assay is rapid and has high throughput.

Catalog number: Technical Support Customer Service. Utilize the globally valued accuracy, precision, lot-to-lot dependability and stable shelf life of CEDIA™ Opiate Drugs of Abuse Assays, which offer applications for an array of clinical chemistry analyzers. The drugs of abuse testing scope is expanding rapidly, and CEDIA assays meet this challenge by offering one of the most extensive menus for drugs of abuse testing and developing new assays to respond to ever-emerging drug. Berg, Schjøtt, Fossan, Riedel: Cross-reactivity of the CEDIA buprenorphine assay in drugs-of-abuse screening: influence of dose and metabolites of opioids, Substance Abuse and Rehabilitation – Like all steroid assays, cross-reactivity of these assays to myriads of natural or synthetic steroids may cause incorrect results. Like the other drugs of use discussed above, the abusers might try to adulterate the specimen to avoid or confuse the assay results.

21 нояб. г. A key attribute of urine drug testing immunoassays is cross-reactivity, namely the response of various compounds compared to the target of. 28 апр. г. Laboratory tests for routine drug of abuse and toxicology These results were compared with cross-reactivity data in the package inserts. SYNCHRON® Systems Drugs of Abuse Testing (DAT) Urine Calibrators are stable until were tested for cross-reactivity with the SYNCHRON Systems AMPH assay.